<?xml version="1.0"?>
 <!DOCTYPE INSDSet PUBLIC "-//NCBI//INSD INSDSeq/EN" "http://www.ncbi.nlm.nih.gov/dtd/INSD_INSDSeq.dtd">
 <INSDSet>
<INSDSeq>
  <INSDSeq_locus>NG_008472</INSDSeq_locus>
  <INSDSeq_length>28136</INSDSeq_length>
  <INSDSeq_strandedness>double</INSDSeq_strandedness>
  <INSDSeq_moltype>DNA</INSDSeq_moltype>
  <INSDSeq_topology>linear</INSDSeq_topology>
  <INSDSeq_division>PRI</INSDSeq_division>
  <INSDSeq_update-date>18-MAY-2014</INSDSeq_update-date>
  <INSDSeq_create-date>09-SEP-2008</INSDSeq_create-date>
  <INSDSeq_definition>Homo sapiens retinal pigment epithelium-specific protein 65kDa (RPE65), RefSeqGene on chromosome 1</INSDSeq_definition>
  <INSDSeq_primary-accession>NG_008472</INSDSeq_primary-accession>
  <INSDSeq_accession-version>NG_008472.1</INSDSeq_accession-version>
  <INSDSeq_other-seqids>
    <INSDSeqid>ref|NG_008472.1|</INSDSeqid>
    <INSDSeqid>gi|198386323</INSDSeqid>
  </INSDSeq_other-seqids>
  <INSDSeq_keywords>
    <INSDKeyword>RefSeq</INSDKeyword>
    <INSDKeyword>RefSeqGene</INSDKeyword>
  </INSDSeq_keywords>
  <INSDSeq_source>Homo sapiens (human)</INSDSeq_source>
  <INSDSeq_organism>Homo sapiens</INSDSeq_organism>
  <INSDSeq_taxonomy>Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo</INSDSeq_taxonomy>
  <INSDSeq_references>
    <INSDReference>
      <INSDReference_reference>1</INSDReference_reference>
      <INSDReference_position>1..28136</INSDReference_position>
      <INSDReference_authors>
        <INSDAuthor>Fahim,A.T.</INSDAuthor>
        <INSDAuthor>Daiger,S.P.</INSDAuthor>
        <INSDAuthor>Weleber,R.G.</INSDAuthor>
      </INSDReference_authors>
      <INSDReference_title>Retinitis Pigmentosa Overview</INSDReference_title>
      <INSDReference_journal>(in) Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)</INSDReference_journal>
      <INSDReference_pubmed>20301590</INSDReference_pubmed>
    </INSDReference>
    <INSDReference>
      <INSDReference_reference>2</INSDReference_reference>
      <INSDReference_position>1..28136</INSDReference_position>
      <INSDReference_authors>
        <INSDAuthor>Weleber,R.G.</INSDAuthor>
        <INSDAuthor>Francis,P.J.</INSDAuthor>
        <INSDAuthor>Trzupek,K.M.</INSDAuthor>
        <INSDAuthor>Beattie,C.</INSDAuthor>
      </INSDReference_authors>
      <INSDReference_title>Leber Congenital Amaurosis</INSDReference_title>
      <INSDReference_journal>(in) Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)</INSDReference_journal>
      <INSDReference_pubmed>20301475</INSDReference_pubmed>
    </INSDReference>
  </INSDSeq_references>
  <INSDSeq_comment>REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL139413.11.; This sequence is a reference standard in the RefSeqGene project.; ~Summary: This gene encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration. There are two forms of this protein, a soluble form called sRPE65, and a palmitoylated, membrane-bound form known as mRPE65. mRPE65 serves as the palmitoyl donor for lecithin retinol acyl transferase (LRAT), the enzyme that catalyzes the vitamin A to all trans retinol step of the chromophore regeneration process. Both mRPE65 and sRPE65 also serve as regulatory proteins, with the ratio and concentrations of these molecules playing a role in the inhibition of 11-cis retinal synthesis. Mutations in this gene have been associated with Leber congenital amaurosis type 2 (LCA2) and retinitis pigmentosa. [provided by RefSeq, Jul 2008]</INSDSeq_comment>
  <INSDSeq_primary>REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP~1-28136             AL139413.11        55251-83386         c</INSDSeq_primary>
  <INSDSeq_feature-table>
    <INSDFeature>
      <INSDFeature_key>source</INSDFeature_key>
      <INSDFeature_location>1..28136</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>1</INSDInterval_from>
          <INSDInterval_to>28136</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>organism</INSDQualifier_name>
          <INSDQualifier_value>Homo sapiens</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>mol_type</INSDQualifier_name>
          <INSDQualifier_value>genomic DNA</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>taxon:9606</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>chromosome</INSDQualifier_name>
          <INSDQualifier_value>1</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>map</INSDQualifier_name>
          <INSDQualifier_value>1p31</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>STS</INSDFeature_key>
      <INSDFeature_location>2179..2368</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>2179</INSDInterval_from>
          <INSDInterval_to>2368</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>standard_name</INSDQualifier_name>
          <INSDQualifier_value>D1S2803</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>UniSTS:1806</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>STS</INSDFeature_key>
      <INSDFeature_location>2187..2457</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>2187</INSDInterval_from>
          <INSDInterval_to>2457</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>standard_name</INSDQualifier_name>
          <INSDQualifier_value>G60461</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>UniSTS:137717</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>STS</INSDFeature_key>
      <INSDFeature_location>3212..3332</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>3212</INSDInterval_from>
          <INSDInterval_to>3332</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>standard_name</INSDQualifier_name>
          <INSDQualifier_value>RH92230</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>UniSTS:89397</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>STS</INSDFeature_key>
      <INSDFeature_location>4985..5137</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>4985</INSDInterval_from>
          <INSDInterval_to>5137</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>standard_name</INSDQualifier_name>
          <INSDQualifier_value>PMC19699P2</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>UniSTS:271837</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>gene</INSDFeature_key>
      <INSDFeature_location>5001..26136</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>5001</INSDInterval_from>
          <INSDInterval_to>26136</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>gene</INSDQualifier_name>
          <INSDQualifier_value>RPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>gene_synonym</INSDQualifier_name>
          <INSDQualifier_value>BCO3; LCA2; mRPE65; rd12; RP20; sRPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>note</INSDQualifier_name>
          <INSDQualifier_value>retinal pigment epithelium-specific protein 65kDa</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>GeneID:6121</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>HGNC:10294</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>MIM:180069</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>mRNA</INSDFeature_key>
      <INSDFeature_location>join(5001..5065,6254..6336,8100..8250,10077..10184,10288..10429,13960..14107,15318..15399,15637..15769,15879..16018,16644..16773,23375..23489,23584..23678,23784..23895,25033..26136)</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>5001</INSDInterval_from>
          <INSDInterval_to>5065</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>6254</INSDInterval_from>
          <INSDInterval_to>6336</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>8100</INSDInterval_from>
          <INSDInterval_to>8250</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>10077</INSDInterval_from>
          <INSDInterval_to>10184</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>10288</INSDInterval_from>
          <INSDInterval_to>10429</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>13960</INSDInterval_from>
          <INSDInterval_to>14107</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>15318</INSDInterval_from>
          <INSDInterval_to>15399</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>15637</INSDInterval_from>
          <INSDInterval_to>15769</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>15879</INSDInterval_from>
          <INSDInterval_to>16018</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>16644</INSDInterval_from>
          <INSDInterval_to>16773</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>23375</INSDInterval_from>
          <INSDInterval_to>23489</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>23584</INSDInterval_from>
          <INSDInterval_to>23678</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>23784</INSDInterval_from>
          <INSDInterval_to>23895</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>25033</INSDInterval_from>
          <INSDInterval_to>26136</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_operator>join</INSDFeature_operator>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>gene</INSDQualifier_name>
          <INSDQualifier_value>RPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>gene_synonym</INSDQualifier_name>
          <INSDQualifier_value>BCO3; LCA2; mRPE65; rd12; RP20; sRPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>product</INSDQualifier_name>
          <INSDQualifier_value>retinal pigment epithelium-specific protein 65kDa</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>transcript_id</INSDQualifier_name>
          <INSDQualifier_value>NM_000329.2</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>GI:67188783</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>GeneID:6121</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>HGNC:10294</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>MIM:180069</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>transcription</INSDQualifier_name>
          <INSDQualifier_value>TCCTTCTTCATTCTGCAGTTGGTGCCAGAACTCTGGATCCTGAACTGGAAGAAAATGTCTATCCAGGTTGAGCATCCTGCTGGTGGTTACAAGAAACTGTTTGAAACTGTGGAGGAACTGTCCTCGCCGCTCACAGCTCATGTAACAGGCAGGATCCCCCTCTGGCTCACCGGCAGTCTCCTTCGATGTGGGCCAGGACTCTTTGAAGTTGGATCTGAGCCATTTTACCACCTGTTTGATGGGCAAGCCCTCCTGCACAAGTTTGACTTTAAAGAAGGACATGTCACATACCACAGAAGGTTCATCCGCACTGATGCTTACGTACGGGCAATGACTGAGAAAAGGATCGTCATAACAGAATTTGGCACCTGTGCTTTCCCAGATCCCTGCAAGAATATATTTTCCAGGTTTTTTTCTTACTTTCGAGGAGTAGAGGTTACTGACAATGCCCTTGTTAATGTCTACCCAGTGGGGGAAGATTACTACGCTTGCACAGAGACCAACTTTATTACAAAGATTAATCCAGAGACCTTGGAGACAATTAAGCAGGTTGATCTTTGCAACTATGTCTCTGTCAATGGGGCCACTGCTCACCCCCACATTGAAAATGATGGAACCGTTTACAATATTGGTAATTGCTTTGGAAAAAATTTTTCAATTGCCTACAACATTGTAAAGATCCCACCACTGCAAGCAGACAAGGAAGATCCAATAAGCAAGTCAGAGATCGTTGTACAATTCCCCTGCAGTGACCGATTCAAGCCATCTTACGTTCATAGTTTTGGTCTGACTCCCAACTATATCGTTTTTGTGGAGACACCAGTCAAAATTAACCTGTTCAAGTTCCTTTCTTCATGGAGTCTTTGGGGAGCCAACTACATGGATTGTTTTGAGTCCAATGAAACCATGGGGGTTTGGCTTCATATTGCTGACAAAAAAAGGAAAAAGTACCTCAATAATAAATACAGAACTTCTCCTTTCAACCTCTTCCATCACATCAACACCTATGAAGACAATGGGTTTCTGATTGTGGATCTCTGCTGCTGGAAAGGATTTGAGTTTGTTTATAATTACTTATATTTAGCCAATTTACGTGAGAACTGGGAAGAGGTGAAAAAAAATGCCAGAAAGGCTCCCCAACCTGAAGTTAGGAGATATGTACTTCCTTTGAATATTGACAAGGCTGACACAGGCAAGAATTTAGTCACGCTCCCCAATACAACTGCCACTGCAATTCTGTGCAGTGACGAGACTATCTGGCTGGAGCCTGAAGTTCTCTTTTCAGGGCCTCGTCAAGCATTTGAGTTTCCTCAAATCAATTACCAGAAGTATTGTGGGAAACCTTACACATATGCGTATGGACTTGGCTTGAATCACTTTGTTCCAGATAGGCTCTGTAAGCTGAATGTCAAAACTAAAGAAACTTGGGTTTGGCAAGAGCCTGATTCATACCCATCAGAACCCATCTTTGTTTCTCACCCAGATGCCTTGGAAGAAGATGATGGTGTAGTTCTGAGTGTGGTGGTGAGCCCAGGAGCAGGACAAAAGCCTGCTTATCTCCTGATTCTGAATGCCAAGGACTTAAGTGAAGTTGCCCGGGCTGAAGTGGAGATTAACATCCCTGTCACCTTTCATGGACTGTTCAAAAAATCTTGAGCATACTCCAGCAAGATATGTTTTTGGTAGCAAAACTGAGAAAATCAGCTTCAGGTCTGCAATCAAATTCTGTTCAATTTTAGCCTGCTATATGTCATGGTTTTAACTTGCAGATGCGCACAATTTTGCAATGTTTTACAGAAAGCACTGAGTTGAGCAAGCAATTCCTTTATTTAAAAAAAAAAGTACGTATTTAGATAATCATACTTCCTCTGTGAGACAGGCCATAACTGAAAAACTCTTAAATATTTAGCAATCAAATAGGAAATGAATGTGGACTTACTAAATGGCTTTTAATTCCTATTATAAGAGCATATTTTAGGTACCTATCTGCTCCAATTATATTTTTAACATTTAAAAACCAAAGTCCTCTACACTTGATTTATATTATATGTGGCTTTGCTGAGTCAAGGAAGTATCATGCAATAAGGCTTAATTACTAAATGTCAAACCAAACTTTTTCTCAAACCAGGGACTATCATCTAAGATTAATTACAGTAATTATTTTGCGTATACGTAACTGCTCAAAGATTATGAATCTTATGAATGTTAACCTTTCCGTTTATTACAAGCAAGTACTATTATTTCTGATTTTATAATAAGAAAATCTGTGTTTAATCAACTGAGGCCTCTCAACCAAATAACATCTCAGAGATTAAGTTATATATTAAAAGCTTATGTAACATAAAAGCAAGTACATATAGTAGTGACTATATTTAAAAAAACAGCATAAAATGCTTAAAAATGTAATATTTACTAAAATCAGATTATGGGATAATGTTGCAGGATTATACTTTATTGCATCTTTTTTGTTTAATTGTATTTAAGCATTGTGCAATCACTTGGGAAAAATATTAAATTATTAACATTGAGGTATTAATACATTTTAAGCCTTTTGTTTTTAAATTTCTTTTCTTCCAGAGATTGTTTAAAAATAAATATTGACAAAAAT</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>exon</INSDFeature_key>
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      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>5001</INSDInterval_from>
          <INSDInterval_to>5065</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>gene</INSDQualifier_name>
          <INSDQualifier_value>RPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>gene_synonym</INSDQualifier_name>
          <INSDQualifier_value>BCO3; LCA2; mRPE65; rd12; RP20; sRPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>inference</INSDQualifier_name>
          <INSDQualifier_value>alignment:Splign:1.39.8</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>number</INSDQualifier_name>
          <INSDQualifier_value>1</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>CDS</INSDFeature_key>
      <INSDFeature_location>join(5055..5065,6254..6336,8100..8250,10077..10184,10288..10429,13960..14107,15318..15399,15637..15769,15879..16018,16644..16773,23375..23489,23584..23678,23784..23895,25033..25184)</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>5055</INSDInterval_from>
          <INSDInterval_to>5065</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>6254</INSDInterval_from>
          <INSDInterval_to>6336</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>8100</INSDInterval_from>
          <INSDInterval_to>8250</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>10077</INSDInterval_from>
          <INSDInterval_to>10184</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>10288</INSDInterval_from>
          <INSDInterval_to>10429</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>13960</INSDInterval_from>
          <INSDInterval_to>14107</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>15318</INSDInterval_from>
          <INSDInterval_to>15399</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>15637</INSDInterval_from>
          <INSDInterval_to>15769</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
          <INSDInterval_from>15879</INSDInterval_from>
          <INSDInterval_to>16018</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
        <INSDInterval>
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        <INSDQualifier>
          <INSDQualifier_name>gene</INSDQualifier_name>
          <INSDQualifier_value>RPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>gene_synonym</INSDQualifier_name>
          <INSDQualifier_value>BCO3; LCA2; mRPE65; rd12; RP20; sRPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>standard_name</INSDQualifier_name>
          <INSDQualifier_value>PMC19699P10</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>UniSTS:271831</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>exon</INSDFeature_key>
      <INSDFeature_location>15879..16018</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>15879</INSDInterval_from>
          <INSDInterval_to>16018</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>gene</INSDQualifier_name>
          <INSDQualifier_value>RPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>gene_synonym</INSDQualifier_name>
          <INSDQualifier_value>BCO3; LCA2; mRPE65; rd12; RP20; sRPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>inference</INSDQualifier_name>
          <INSDQualifier_value>alignment:Splign:1.39.8</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>number</INSDQualifier_name>
          <INSDQualifier_value>9</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>STS</INSDFeature_key>
      <INSDFeature_location>16602..16799</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>16602</INSDInterval_from>
          <INSDInterval_to>16799</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>gene</INSDQualifier_name>
          <INSDQualifier_value>RPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>gene_synonym</INSDQualifier_name>
          <INSDQualifier_value>BCO3; LCA2; mRPE65; rd12; RP20; sRPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>standard_name</INSDQualifier_name>
          <INSDQualifier_value>PMC19699P11</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>UniSTS:271832</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>exon</INSDFeature_key>
      <INSDFeature_location>16644..16773</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>16644</INSDInterval_from>
          <INSDInterval_to>16773</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>gene</INSDQualifier_name>
          <INSDQualifier_value>RPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>gene_synonym</INSDQualifier_name>
          <INSDQualifier_value>BCO3; LCA2; mRPE65; rd12; RP20; sRPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>inference</INSDQualifier_name>
          <INSDQualifier_value>alignment:Splign:1.39.8</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>number</INSDQualifier_name>
          <INSDQualifier_value>10</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>exon</INSDFeature_key>
      <INSDFeature_location>23375..23489</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>23375</INSDInterval_from>
          <INSDInterval_to>23489</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>gene</INSDQualifier_name>
          <INSDQualifier_value>RPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>gene_synonym</INSDQualifier_name>
          <INSDQualifier_value>BCO3; LCA2; mRPE65; rd12; RP20; sRPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>inference</INSDQualifier_name>
          <INSDQualifier_value>alignment:Splign:1.39.8</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>number</INSDQualifier_name>
          <INSDQualifier_value>11</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>STS</INSDFeature_key>
      <INSDFeature_location>23552..23727</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>23552</INSDInterval_from>
          <INSDInterval_to>23727</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>gene</INSDQualifier_name>
          <INSDQualifier_value>RPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>gene_synonym</INSDQualifier_name>
          <INSDQualifier_value>BCO3; LCA2; mRPE65; rd12; RP20; sRPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>standard_name</INSDQualifier_name>
          <INSDQualifier_value>PMC19699P12</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>UniSTS:271833</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>exon</INSDFeature_key>
      <INSDFeature_location>23584..23678</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>23584</INSDInterval_from>
          <INSDInterval_to>23678</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>gene</INSDQualifier_name>
          <INSDQualifier_value>RPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>gene_synonym</INSDQualifier_name>
          <INSDQualifier_value>BCO3; LCA2; mRPE65; rd12; RP20; sRPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>inference</INSDQualifier_name>
          <INSDQualifier_value>alignment:Splign:1.39.8</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>number</INSDQualifier_name>
          <INSDQualifier_value>12</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>STS</INSDFeature_key>
      <INSDFeature_location>23739..23937</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>23739</INSDInterval_from>
          <INSDInterval_to>23937</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>gene</INSDQualifier_name>
          <INSDQualifier_value>RPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>gene_synonym</INSDQualifier_name>
          <INSDQualifier_value>BCO3; LCA2; mRPE65; rd12; RP20; sRPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>standard_name</INSDQualifier_name>
          <INSDQualifier_value>PMC19699P13</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>UniSTS:271834</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>exon</INSDFeature_key>
      <INSDFeature_location>23784..23895</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>23784</INSDInterval_from>
          <INSDInterval_to>23895</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>gene</INSDQualifier_name>
          <INSDQualifier_value>RPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>gene_synonym</INSDQualifier_name>
          <INSDQualifier_value>BCO3; LCA2; mRPE65; rd12; RP20; sRPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>inference</INSDQualifier_name>
          <INSDQualifier_value>alignment:Splign:1.39.8</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>number</INSDQualifier_name>
          <INSDQualifier_value>13</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>STS</INSDFeature_key>
      <INSDFeature_location>24900..25077</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>24900</INSDInterval_from>
          <INSDInterval_to>25077</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>gene</INSDQualifier_name>
          <INSDQualifier_value>RPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>gene_synonym</INSDQualifier_name>
          <INSDQualifier_value>BCO3; LCA2; mRPE65; rd12; RP20; sRPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>standard_name</INSDQualifier_name>
          <INSDQualifier_value>PMC19699P14</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>UniSTS:271835</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>exon</INSDFeature_key>
      <INSDFeature_location>25033..26136</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>25033</INSDInterval_from>
          <INSDInterval_to>26136</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>gene</INSDQualifier_name>
          <INSDQualifier_value>RPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>gene_synonym</INSDQualifier_name>
          <INSDQualifier_value>BCO3; LCA2; mRPE65; rd12; RP20; sRPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>inference</INSDQualifier_name>
          <INSDQualifier_value>alignment:Splign:1.39.8</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>number</INSDQualifier_name>
          <INSDQualifier_value>14</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>STS</INSDFeature_key>
      <INSDFeature_location>25033..25401</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>25033</INSDInterval_from>
          <INSDInterval_to>25401</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>gene</INSDQualifier_name>
          <INSDQualifier_value>RPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>gene_synonym</INSDQualifier_name>
          <INSDQualifier_value>BCO3; LCA2; mRPE65; rd12; RP20; sRPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>standard_name</INSDQualifier_name>
          <INSDQualifier_value>PMC19699P1</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>UniSTS:271830</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>STS</INSDFeature_key>
      <INSDFeature_location>25033..25241</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>25033</INSDInterval_from>
          <INSDInterval_to>25241</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>gene</INSDQualifier_name>
          <INSDQualifier_value>RPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>gene_synonym</INSDQualifier_name>
          <INSDQualifier_value>BCO3; LCA2; mRPE65; rd12; RP20; sRPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>standard_name</INSDQualifier_name>
          <INSDQualifier_value>PMC19699P15</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>UniSTS:271836</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>STS</INSDFeature_key>
      <INSDFeature_location>25187..25410</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>25187</INSDInterval_from>
          <INSDInterval_to>25410</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>gene</INSDQualifier_name>
          <INSDQualifier_value>RPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>gene_synonym</INSDQualifier_name>
          <INSDQualifier_value>BCO3; LCA2; mRPE65; rd12; RP20; sRPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>standard_name</INSDQualifier_name>
          <INSDQualifier_value>SHGC-31528</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>UniSTS:17539</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
    <INSDFeature>
      <INSDFeature_key>STS</INSDFeature_key>
      <INSDFeature_location>25215..25461</INSDFeature_location>
      <INSDFeature_intervals>
        <INSDInterval>
          <INSDInterval_from>25215</INSDInterval_from>
          <INSDInterval_to>25461</INSDInterval_to>
          <INSDInterval_accession>NG_008472.1</INSDInterval_accession>
        </INSDInterval>
      </INSDFeature_intervals>
      <INSDFeature_quals>
        <INSDQualifier>
          <INSDQualifier_name>gene</INSDQualifier_name>
          <INSDQualifier_value>RPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>gene_synonym</INSDQualifier_name>
          <INSDQualifier_value>BCO3; LCA2; mRPE65; rd12; RP20; sRPE65</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>standard_name</INSDQualifier_name>
          <INSDQualifier_value>RH80292</INSDQualifier_value>
        </INSDQualifier>
        <INSDQualifier>
          <INSDQualifier_name>db_xref</INSDQualifier_name>
          <INSDQualifier_value>UniSTS:86124</INSDQualifier_value>
        </INSDQualifier>
      </INSDFeature_quals>
    </INSDFeature>
  </INSDSeq_feature-table>
  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</INSDSeq>

</INSDSet>